Orelabrutinib er en tablet, der tages gennem munden. I dette forsøg bliver den undersøgt som en mulig behandling til personer med primær progressiv multipel sklerose. Formålet er at se, om den kan hjælpe med at bremse forværring af handicap og sygdomsudvikling sammenlignet med ingen aktiv behandling.

Primary Progressive Multiple Sclerosis – A chronic disease of the nervous system in which symptoms gradually worsen from the start without clear periods of recovery. It happens because the protective covering of nerve fibers is damaged, which slows or disrupts nerve signals. Over time, this can lead to increasing problems with walking, balance, strength, coordination, and hand function. The course is usually slowly progressive, with disability building up step by step.